A Role for Mammi

Clinical Images 3D View. Courtesy of Dr. R. Valdés Olmos, Netherlands Cancer Institute, Amsterdam

Adding it all together: a role for MAMMI Breast PET

Several clinically proven options are available today to help women in the more advanced breast cancer centers around the World.

The Innovate PET MAMMI is now one more, with some significant differences vs former options:

PEM or MRI...
MRI is an excellent morphological (anatomical) exploration. It has high sensitivity and excellent resolution, and it is used today in the assessment of younger women from groups of risk. It does generate, however, a significant number of false positives. PEM has good, comparable sensitivity and higher specificity, reducing the number of false positives. Quantification of tumor activity, related to the physiological imaging capability of PEM, having fewer patient restrictions than MRI (obesity, implants...) and fast speed, together with freeing MRI time for other explorations are also factors to be considered.

PEM or whole body PET...
Both types are complementary. The improved resolution and the lower radiation dosage of PEM vs Whole-body PET, the flexibility of having a dedicated unit in high volume centers vs the pressure by multiple specialties in using PET and, specially, the fast and clear assessment of results of chemotherapy and other treatments, and the study of younger women or women with dense breasts with reduced radiation dosage are fields of indication.

PEM vs BSGI
BSGI is also a valuable breast exploration, with good resolution, used as complementary to X-Ray mammography in some centers. PEM´s accurate quantification, excellent resolution, MAMMI´s prone posititon and no breast compression for improved patient comfort, access to difficult lesions and in small
breasts, very fast explorations and reduced radiation dosage are points to be possibly considered.

MAMMI vs other PEM
MAMMI´s exclusive continuous crystal technology, with related improved resolution, excellent sensitivity, very fast explorations and reconstructions, prone posititon and no breast compression for improved patient comfort, access to difficult lesions and in small breasts, very fast explorations and reduced radiation dosage are possible relevant differences.

MAMMI: Performance Delivered

MAMMI: More accurate than Whole-body PET in advanced tumors

MAMMI has been directly evaluated, during its clinical development, against prestigious and state-of-the-art Whole-body PET, with excellent comparative results in sensitivity and, specially, significantly improved resolution, speed and ease of use, as well as excellent performance significantly reducing (often lower than 50%) tracer dosage.

MAMMI is not defined as a substitute for Whole-body PET units, useful for multiple other Whole-body applications. MAMMI´s superior performance in breast pathologies is complementary of standard Whole-body PET at major Institutions, and can be of definitive independent value in Centers with access to Whole-body PET explorations when needed during patient evolution.

Prone position for optimum tumor (and other pathologies) identification

Supine vs Prone position: a major clinical difference

Prone position does not only bring significantly improved comfort to every woman, by avoiding any breast compression, this being important. The MAIN difference is the greatly improved clinical localization and clear topographic identification of lesions, which can impact treatment, as well as the more correct anatomical correlation of images with actual anatomy, specially valuable for surgery. For this same reason, the prone position has been also adopted by MRI and stereotactic digital X-Ray tables, often requiring, however, breast compresion, which MAMMI does not need.